A study from the journal Neurology revealed that nonalcoholic fatty liver disease (NAFLD) is independently associated with cognitive impairment.
Nonalcoholic fatty liver disease (NAFLD) is an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. As the name implies, the main characteristic of NAFLD is too much fat stored in liver cells.
Dementia and NAFLD are two frequent conditions that share underlying risk factors mainly in the realm of metabolic disease.
The study from the journal Neurology included 4,472 adults age 20–59 years. The participants underwent assessment of liver enzyme activity and hepatic steatosis by ultrasound, and underwent cognitive evaluation using the following computer-administered tests: Simple Reaction Time Test (SRTT), Symbol-Digit Substitution Test (SDST), and Serial Digit Learning Test (SDLT).
Increased activity of the liver enzymes alanine aminotransferase (ALT) and aspartate aminotransferase (AST) correlated with while increased alanine aminotransferase was also correlated with lower performance in the SDST.
The current studies suggest that patients diagnosed with NAFLD incur cognitive dysfunction.
If left untreated, NAFLD can lead to more serious conditions including cirrhosis and liver failure. The good news is that fatty liver disease can be reversed—and even cured.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820136/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7400092/
https://aasldpubs.onlinelibrary.wiley.com/doi/pdf/10.1002/hep.22752
https://www.hindawi.com/journals/grp/2016/1459790/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789322/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165515/
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